Who Is Anxiety Medication Right For?
Anxiety is worry or fear that can range from mild to severe.1 Anxiety is a normal part of life and many people experience it from time to time. However, if anxiety becomes excessive and interferes with your functioning, then you might have an anxiety disorder.
There are several different types of anxiety disorders, including generalized anxiety, social anxiety, and panic disorder. When anxiety reaches the point of becoming a disorder, treatment may be necessary. Anxiety treatment may include therapy, medication, or both, and talk to your general practitioner or a psychiatrist about starting anxiety medication.
Do Anxiety Meds Work Immediately?
The rate at which you will feel the effects of anxiety medication depends on the specific medication. Some medications work rather quickly at reducing anxiety symptoms, while others can take much longer. Benzodiazepines are one type of anxiety medication that provide immediate relief.2,3 These medications are often prescribed as-needed (PRN) for a short period of time. They can help reduce symptoms of anxiety and panic attacks fairly quickly, like intense worry, racing heart, and shaking.
Antidepressants are a group of medications used to treat both depression and anxiety.2 They can help reduce symptoms of long-term anxiety, like those of generalized anxiety disorder. These medications do not reduce symptoms immediately like benzodiazepines. They can take around four to six weeks to have full effect.
Medication for Short-Term Anxiety Relief
Short-term anxiety medications are used to treat acute anxiety and panic attacks.2 These medications can help alleviate extreme fear and physical symptoms of panic attacks, like rapid heart rate and sweating. People with social anxiety and phobias may also benefit from taking short-term anxiety medications in situations where they anticipate feeling overwhelmed.
There are several different types of short-term anxiety medications, including benzodiazepines, beta blockers, and an antihistamine called hydroxyzine.2,3,4 While these medications can all help alleviate acute fear and anxiety, there are some differences.
Beta blockers are effective at reducing the physical symptoms of anxiety, while benzodiazepines can help with both emotional and physical symptoms. Beta blockers may be preferred because they cause fewer side effects and pose less danger than benzodiazepines. They are considered to be safer for children, teens, and pregnant women. Depending on the specific type of short-term anxiety medication, it can take a few minutes to an hour or more to feel the effects, and effects may vary from individual to individual.3,5,6
The most common benzodiazepines prescribed for short-term anxiety include:3
- Alprazolam (Xanax)*
- Clonazepam (Klonopin)*
- Lorazepam (Ativan)*
- Diazepam (Valium)*
*These medications have a black box warning, the most serious kind of warnings from the FDA for abuse or misuse, risk of physical dependence, and risk of serious side effects, including death, when combined with an opioid.
When Will Short-Term Anxiety Meds Kick In?
How quickly you can expect to feel the effects of short-term anxiety medication will depend on the specific medication. Benzodiazepines, beta blockers, and antihistamines vary in how quickly they work and how long the effects last.3,5,6 Even different types of benzodiazepines differ in their onset time.3
Here’s a general timeline when you might expect to see results from short-term anxiety medication:5,6,7
- 30 minutes – If you have taken a benzodiazepine or antihistamine you will start to feel the effects of the medication and should experience relief.
- 1 hour – If you have taken a beta blocker you should begin to feel the effects.
- 2 hours – You may continue to feel the effects of the medication, but they are likely starting to wear off.
- 4-6 hours – Depending on the medication, you may still feel some of the effects.
- 24 hours – You will no longer feel the effects of the medication, though it is likely to still be detectable in your body.
Signs Your Anxiety Meds Are Working
Short-term anxiety medications provide quick relief from the emotional and physical symptoms of anxiety. Within minutes to one hour you should feel less anxious and more calm.5,6,7
Some signs your short term anxiety meds have started working may include:2
- Less anxiety and fear
- Feelings of calm and relaxation
- Decreased heart rate
- Decreased sweating
- Less shaking
Side Effects from Short-Term Anti-Anxiety Medication
Common side effects of short-term anxiety medications include fatigue, confusion, headache, blurry vision, nausea, and nightmares.2 These side effects may begin shortly after taking the medication. Long-term use of benzodiazepines can cause cognitive decline and worsen dementia in older adults.3
Be sure to talk to your doctor about any side effects that you are experiencing. If you experience swelling, rash, hives, yellowing of the skin or eyes, trouble breathing, suicidal thoughts, or seizures, talk to your doctor right away.
How Long Should You Take Fast Acting Anxiety Medication?
Benzodiazepines are intended to be taken as-needed (PRN), rather than as a daily medication.3 These medications provide benefits rather quickly, which makes them helpful for panic attacks. Because long-term use of these medications can lead to addiction, dependence, and memory issues, they are usually only prescribed for short periods of time.
Chronic anxiety is treated with antidepressants or buspirone (Buspar).2 If you are taking or considering taking benzodiazepines, speak to your doctor and treatment team to come up with a plan that works for you.
anxiety
Anxiety Medication
Are anti-anxiety drugs right for you? Learn about common side effects, risks, and how to take them responsibly.
The role of medication in anxiety treatment
When you’re overwhelmed by heart-pounding panic, paralyzed by fear, or exhausted from yet another sleepless night spent worrying, you’ll do just about anything to get relief. And there’s no question that when anxiety is disabling, medication may help. But are drugs always the best answer?
Many different types of medications are used in the treatment of anxiety disorders, including traditional anti-anxiety drugs such as benzodiazepines (typically prescribed for short-term use) and newer options like SSRI antidepressants (often recommended as a long-term anxiety solution). These drugs can provide temporary relief, but they also come with side effects and safety concerns—some significant.
They are also not a cure. In fact, there are many questions about their long-term effectiveness. According to the American Academy of Family Physicians, benzodiazepines lose their therapeutic anti-anxiety effect after 4 to 6 months of regular use. And a recent analysis reported in JAMA Psychiatry found that the effectiveness of SSRIs in treating anxiety has been overestimated, and in some cases is no better than placebo.
What’s more, it can be very difficult to get off anxiety medications without difficult withdrawals, including rebound anxiety that can be worse than your original problem.
I need relief, and I need it now!
So where does that leave you if you’re suffering? Even when anxiety relief comes with side effects and dangers, that can still sound like a fair trade when panic and fear are ruling your life.
The bottom line is that there’s a time and place for anxiety medication. If you have severe anxiety that’s interfering with your ability to function, medication may be helpful—especially as a short-term treatment. However, many people use anti-anxiety medication when therapy, exercise, or other self-help strategies would work just as well or better, minus the drawbacks.
Anxiety medications can ease symptoms, but they’re not right for everyone and they’re not the only answer. It’s up to you to evaluate your options and decide what’s best for you.
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Benzodiazepines for anxiety
Benzodiazepines (also known as tranquilizers) are the most widely prescribed type of medication for anxiety. Drugs such as Xanax (alprazolam), Klonopin (clonazepam), Valium (diazepam), and Ativan (lorazepam) work quickly, typically bringing relief within 30 minutes to an hour. That makes them very effective when taken during a panic attack or another overwhelming anxiety episode. However, they are physically addictive and not recommended for long-term treatment.
Benzodiazepines work by slowing down the nervous system, helping you relax both physically and mentally. But it can also lead to unwanted side effects. The higher the dose, the more intense these side effects typically are—although some people feel sleepy, foggy, and uncoordinated even on low doses. This can cause problems with work, school, or everyday activities such as driving. The medication hangover can last into the next day.
Common side effects of benzodiazepines include:
- Drowsiness
- Dizziness
- Poor balance or coordination
- Slurred speech
- Trouble concentrating
- Memory problems
- Confusion
- Stomach upset
- Headache
- Blurred vision
Benzodiazepines can make depression worse
According to the FDA, benzodiazepines can worsen cases of pre-existing depression, and more recent studies suggest that they may potentially lead to treatment-resistant depression. Furthermore, benzodiazepines can cause emotional blunting or numbness and increase suicidal thoughts and feelings.
Benzodiazepine safety concerns
Benzodiazepines are generally not recommended for long-term use since the safety concerns and risk of abuse increase as you build up a tolerance to the medication.
Drug dependence and withdrawal
When taken regularly, benzodiazepines lead to physical dependence and tolerance, with increasingly larger doses needed to get the same anxiety relief as before. This happens quickly—usually within a couple of months, but sometimes in as little as a few weeks.
If you abruptly stop taking your medication, you may experience severe withdrawal symptoms such as:
- Increased anxiety, restlessness, shaking.
- Insomnia, confusion, stomach pain.
- Depression, confusion, panic attacks.
- Pounding heart, sweating, and in severe cases, seizure.
Many people mistake withdrawal symptoms for a return of their original anxiety condition, making them think they need to restart the medication. Gradually tapering off the drug will help minimize the withdrawal reaction.
Drug interactions and overdose
While benzodiazepines are relatively safe when taken only occasionally and in small doses, they can be dangerous and even deadly when combined with other central nervous system depressants. Always talk to your doctor or pharmacist before combining medications.
Don’t drink on benzodiazepines. When mixed with alcohol, benzodiazepines can lead to fatal overdose.
Don’t mix with painkillers or sleeping pills. Taking benzodiazepines with prescription pain or sleeping pills can also lead to fatal overdose.
Antihistamines amplify their effects. Antihistamines—found in many over-the-counter sleep, cold, and allergy medicines—are sedating on their own. Be cautious when mixing with benzodiazepines to avoid over-sedation.
Be cautious when combining with antidepressants. SSRIs such as Prozac and Zoloft can heighten benzodiazepine toxicity. You may need to adjust your dose accordingly.
Paradoxical effects of benzodiazepines
The benzodiazepines work because they slow down the nervous system. But sometimes, for reasons that aren’t well understood, they have the opposite effect. Paradoxical reactions are most common in children, the elderly, and people with developmental disabilities. They include:
- Increased anxiety, irritability, agitation, aggression, and rage
- Mania, impulsive behavior, and hallucinations
Special benzodiazepine risk factors
Anyone who takes benzodiazepines can experience unpleasant or dangerous side effects. But certain individuals are at a higher risk:
People over 65. Older adults are more sensitive to the sedating effects of benzodiazepines. Even small doses can cause confusion, amnesia, loss of balance, and cognitive impairment that looks like dementia. Benzodiazepine use in the elderly is associated with an increased risk of falls, broken hips and legs, and car accidents. Long-term benzodiazepine use also increases the risk of Alzheimer’s disease and dementia.
People with a history of substance abuse. Because they’re physically addicting and on their own and dangerous when combined with alcohol and other drugs, anyone with a current or former substance abuse problem should use benzodiazepines only with extreme caution.
Pregnant and breastfeeding women. Benzodiazepine use during pregnancy can lead to dependence in the developing baby, with withdrawal following birth. Benzodiazepines are also excreted in breast milk. Therefore, pregnant women need to have a thorough discussion about the risks and benefits of these medications with their prescribing doctor. If medication is necessary, the goal is the smallest effective dose.
The connection between benzodiazepines and accidents
Benzodiazepines cause drowsiness and poor coordination, which increases your risk for accidents at home, at work, and on the road. When on benzodiazepines, be very careful when driving, operating machinery, or doing anything else that requires physical coordination.
SSRI antidepressants for anxiety
Many medications originally approved for the treatment of depression are also prescribed for anxiety. In comparison to benzodiazepines, the risk for dependency and abuse is smaller. However, antidepressants take up to 4 to 6 weeks to begin relieving anxiety symptoms, so they can’t be taken “as needed.” Their use is limited to chronic anxiety problems that require ongoing treatment.
The antidepressants most widely prescribed for anxiety are SSRIs such as Prozac, Zoloft, Paxil, Lexapro, and Celexa. SSRIs have been used to treat generalized anxiety disorder (GAD), obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, and post-traumatic stress disorder.
Common side effects of SSRIs include:
- Fatigue
- Nausea
- Agitation
- Drowsiness
- Weight gain
- Diarrhea
- Insomnia
- Sexual dysfunction
- Nervousness
- Headaches
- Dry mouth
- Increased sweating
SSRI withdrawal
Although physical dependence is not as quick to develop with antidepressants, withdrawal can still be an issue. If discontinued too quickly, antidepressant withdrawal can trigger symptoms such as extreme depression and fatigue, irritability, anxiety, flu-like symptoms, and insomnia.
Antidepressant medication and suicide risk
Antidepressants can make depression worse rather than better for some people, leading to an increased risk of suicide, hostility, and even homicidal behavior. While this is particularly true of children and young adults, anyone taking antidepressants should be closely watched. Monitoring is especially important if this is the person’s first time on depression medication or if the dose has recently been changed.
Signs that medication is making things worse include anxiety, panic attacks, insomnia, hostility, restlessness, and extreme agitation—particularly if the symptoms appear suddenly or rapidly deteriorate. If you spot the warning signs in yourself or a loved one, contact a doctor or therapist immediately.
If you are concerned that a friend or family member is contemplating suicide, see Suicide Prevention. The suicide risk is greatest during the first two months of antidepressant treatment.
Other types of medication for anxiety
Drugs such as buspirone, beta blockers, and bupropion may also be used in the treatment of anxiety.
Buspirone (BuSpar)
Buspirone, also known by the brand name BuSpar, is a newer anti-anxiety drug that acts as a mild tranquilizer. Buspirone relieves anxiety by increasing serotonin in the brain—as the SSRIs do—and decreasing dopamine. Compared to benzodiazepines, buspirone is slow acting—taking about two weeks to start working. However, it’s not as sedating, it doesn’t impair memory and coordination, and the withdrawal effects are minimal.
Since the risk of dependence is low and it has no serious drug interactions, buspirone is a better option for older individuals and people with a history of substance abuse. However, its effectiveness is limited. It works for generalized anxiety disorder (GAD), but doesn’t seem to help other types of anxiety disorders.
Common side effects of buspirone include:
- Nausea
- Headaches
- Dizziness
- Drowsiness
- Weight gain
- Upset stomach
- Constipation
- Nervousness
- Diarrhea
- Dry mouth
Beta blockers
Beta blockers—including drugs such as propranolol (Inderal) and atenolol (Tenormin)—are a type of medication used to treat high blood pressure and heart problems. However, they are also prescribed off-label for anxiety. Beta blockers work by blocking the effects of norepinephrine, a stress hormone involved in the fight-or-flight response. This helps control the physical symptoms of anxiety such as rapid heart rate, a trembling voice, sweating, dizziness, and shaky hands.
Because beta blockers don’t affect the emotional symptoms of anxiety such as worry, they’re most helpful for phobias, particularly social phobia and performance anxiety. If you’re anticipating a specific anxiety-producing situation (such as giving a speech), taking a beta blocker in advance can help reduce your “nerves.”
Common side effects of beta blockers include:
- Dizziness
- Sleepiness
- Weakness
- Fatigue
- Nausea
- Headache
- Constipation
- Diarrhea
Bupropion
Bupropion (known by the brand names Wellbutrin, Forfivo, and Zyban) is an antidepressant. However, there is some evidence that it may also be a useful treatment option for anxiety and panic disorders.
Depending on the dosage, in some people bupropion can actually worsen anxiety (as can other antidepressants). However, in others, it can help with generalized anxiety and anxiety symptoms that co-occur with depression. Some trials show that it may be as effective as SSRIs in treating depression with anxiety.
Some common side effects of bupropion include:
- Dizziness
- Nausea
- Dry mouth
- Drowsiness
- Anxiety
- Insomnia
- Loss of appetite
- Headache
Hydroxyzine
Hydroxyzine is an antihistamine often used to relieve allergic reactions. However, it can also be used to treat anxiety symptoms such as tension and nervousness. It works by altering the body’s levels of histamine and serotonin, leading to changes in mood. It’s typically prescribed as a short-term solution, meaning you only use the medication when anxiety symptoms appear.
One 2020 study found that when it comes to treating generalized anxiety disorder, hydroxyzine might be similar in efficacy as benzodiazepines and buspirone.
Common side effects of hydroxyzine include:
- Dry mouth
- Dizziness and confusion
- Headache
- Constipation
- Drowsiness
Medication isn’t your only option for anxiety relief
Anxiety medication won’t solve your problems if you’re anxious because of mounting bills, a tendency to jump to “worst-case scenarios”, or an unhealthy relationship. That’s where self-help, therapy, and other lifestyle changes come in. These non-drug treatments can produce lasting changes and long-term relief.
Exercise – Exercise is a powerful anxiety treatment. Studies show that regular workouts can ease symptoms just as effectively as medication.
Worry busting strategies – You can train your brain to stop worrying and look at life from a more calm and balanced perspective.
Therapy – Cognitive behavioral therapy can teach you how to control your anxiety levels, stop worrisome thoughts, and conquer your fears.
Yoga and tai chi – Yoga and tai chi are mind-body interventions that engage you emotionally, psychologically, and spiritually. Data has shown their efficacy for many different medical conditions, including anxiety.
Mindfulness and meditation – Mindfulness is a state of mind where you learn to observe your thoughts, feelings, and behaviors in a present, compassionate, and non-judgmental way. It often brings a sense of calm and relaxation.
Deciding if anxiety medication is right for you
If you’re trying to decide whether or not to treat your anxiety with medication, it’s important to weigh the pros and cons in conjunction with your doctor. It’s also important to learn about the common side effects of the anxiety medication you are considering. Side effects of anxiety medication range from mild nuisances such as dry mouth to more severe problems such as acute nausea or pronounced weight gain. For any anxiety medication, you will have to balance the side effects against the benefits.
Questions to ask yourself and a mental health professional
- Is medication the best option for my anxiety problem?
- Am I willing to put up with unpleasant side effects in return for anxiety relief?
- What non-drug treatments for anxiety might help?
- Do I have the time and am I willing to pursue non-drug treatments such as cognitive-behavioral therapy?
- What self-help strategies might help me get my anxiety under control?
- If I decide to take anxiety medication, should I pursue other therapy as well?
- Is anxiety really my problem? Or is something else going on, such as an underlying health condition or pain, for example?
Questions to ask your doctor
- How will the medication help my anxiety?
- What are the drug’s common side effects?
- Are there any food and drinks I will need to avoid?
- How will this drug interact with my other prescriptions?
- How long will I have to take the anxiety medication?
- Will withdrawing from the medication be difficult?
- Will my anxiety return when I stop taking the medication?
Authors: Melinda Smith, M.A., Lawrence Robinson, and Jeanne Segal, Ph.D. Reviewed by Anna Glezer, M.D.
Anna Glezer, M.D. is a Harvard-trained clinician with joint appointments in the reproductive psychiatry and OB/GYN departments at UCSF Medical Center. She is the founder of Mind Body Pregnancy.
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Get more help
Medication Options – What you should know when talking with your health care provider. (Anxiety and Depression Association of America)
Benzodiazepines: Side Effects, Abuse Risk and Alternatives – Article written for health care professionals on the benefits and risks of benzodiazepines. (American Family Physician)
Anxiety – Worksheet to help you cope. (Centre for Clinical Interventions)
